GI Genius™ System Improves Adenoma Detection in Real-World Study
News related to:Cosmo N.V · 2 min read
Cosmo N.V., a life sciences company based in Dublin, Ireland, has announced the results of its largest real-world study of the GI Genius™ Intelligent Endoscopy System. The study, published in the journal Gastroenterology, demonstrates that the use of this AI-assisted endoscopy system can significantly improve adenoma detection rates in routine clinical practice.
The study, led by Dominitz et al., involved more than 334,000 colonoscopy procedures performed by 816 endoscopists across 139 U.S. Veterans Health Administration facilities. Among these, 42 facilities (269 endoscopists) had access to the GI Genius™ system, while 97 facilities (547 endoscopists) served as controls.
The findings showed that the availability of the GI Genius™ system was associated with a 22% higher odds of detecting an adenoma (adjusted odds ratio 1.22; 95% confidence interval 1.15 to 1.28). This resulted in an Adenoma Detection Rate (ADR) increase from 50.7% to 54.9% at the sites using the system. Importantly, improvements were observed across endoscopists of all baseline detection rates and levels of experience, indicating that the benefit was not limited to lower performers.
Nhan Ngo Dinh, President of MedTech AI at Cosmo, expressed excitement about the results.
Following the completion of the study, the U.S. Department of Veterans Affairs expanded the deployment of computer-aided detection across all of its colonoscopy facilities. This move underscores the potential of the technology to improve patient outcomes and reduce the burden of colorectal cancer.
The GI Genius™ System is an artificial intelligence-assisted endoscopy system developed by Cosmo and commercialized by Medtronic. It provides real-time computer-aided detection of colorectal polyps during colonoscopy to support physicians in lesion detection and quality improvement during routine clinical practice. The system is not intended to replace clinical decision making.
The study evaluated the impact of the GI Genius™ system on the Adenoma Detection Rate and showed that the availability of the GI Genius™ system was associated with 22% higher odds of detecting an adenoma (adjusted OR 1.22; 95% CI 1.15 to 1.28), with Adenoma Detection Rate rising from 50.7% to 54.9% at CADe sites. Improvements were seen across endoscopists of all baseline detection rates and levels of experience, and were not moderated by specialty or sex, indicating the benefit was not limited to lower performers.
The findings support that improvements in adenoma detection observed in previous randomized studies can also be achieved under routine clinical practice conditions. Following completion of the study, the Veterans Health Administration expanded deployment of computer-aided detection across all of its colonoscopy facilities.