Circle CVI Joins EXIT-CVD Consortium to Advance Personalized Cardiac Care

Circle Cardiovascular Imaging (Circle CVI) has joined a major European research consortium, EXIT-CVD, to advance personalized cardiovascular care through imaging-informed interventions. The five-year project, involving 42 public and private partners from 17 countries, aims to improve patient outcomes by preventing cardiovascular disease progression and reversing established conditions.

Led by the University Medical Center Groningen (UMCG) and Philips, EXIT-CVD will conduct 22 clinical studies involving over 14,000 patients. The project's first patients are set to be enrolled this month, marking a significant step in transforming cardiac care across Europe. The total budget for the initiative is EUR 27.6 million, co-funded by the European Union’s Innovative Health Initiative (IHI) and industry partners.

The consortium’s focus is on early detection, personalized risk assessment, and imaging-guided care. Circle CVI, a provider of AI-enabled cardiovascular imaging software, brings its expertise in AI-enabled cardiovascular MR and CT image analysis to the project. This will support the development of earlier diagnosis, personalized risk assessment, and imaging-guided care strategies.

Cardiovascular health is fundamental to overall well-being, yet more than 60 million people in the European Union are living with cardiovascular disease. Without early detection, timely diagnosis, and appropriate treatment, the condition can significantly reduce quality of life and well-being.

The EXIT-CVD clinical studies will focus on three key exit points along the cardiac care journey: early detection through digital monitoring, personalized risk assessment and targeted interventions, and advanced therapies to support recovery in later-stage disease. By combining diagnostics, digital tools, and advanced therapeutic approaches, the project aims to deliver actionable, evidence-based strategies that can be implemented across diverse healthcare systems in Europe.

The project will embed implementation science and equity-by-design principles to ensure that the solutions are scalable, sustainable, and accessible to all relevant populations, including those historically underserved. A digitally enabled, FAIR-compliant data platform aligned with the European Health Data Space (EHDS) will support the integration, evaluation, and real-world scalability of the project's innovations.

The project is supported by the Innovative Health Initiative Joint Undertaking (IHI JU) under grant agreement No 101253160. The JU receives support from the European Union's Horizon Europe research and innovation program and COCIR, EFPIA, Europa Bío, MedTech Europe, and Vaccines Europe. Funded by the European Union, the private members, and those contributing partners of the IHI JU, the project aims to revolutionize cardiovascular care across Europe.